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<publisher>HAL CCSD</publisher>
<title lang=en>Fever in hospitalized HIV-infected patients in Western French Guiana: first think histoplasmosis</title>
<creator>Vantilcke, Vincent</creator>
<creator>Boukhari, Rachida</creator>
<creator>Jolivet, Anne</creator>
<creator>Vautrin, Cyrille</creator>
<creator>Misslin, Caroline</creator>
<creator>Adenis, Antoine</creator>
<creator>Nacher, Mathieu</creator>
<contributor>Service de Médecine ; Centre Hospitalier de l'Ouest Guyanais Franck Joly (Saint-Laurent-du-Maroni) </contributor>
<contributor>Laboratoire de Biologie Médicale ; Centre Hospitalier de l'Ouest Guyanais Franck Joly (Saint-Laurent-du-Maroni)</contributor>
<contributor>Centre d'investigation clinique Antilles-Guyane ; Institut National de la Santé et de la Recherche Médicale (INSERM) - CH Cayenne</contributor>
<contributor>Centre d'Investigation Clinique Antilles-Guyane (CIC - Antilles Guyane) ; Université des Antilles et de la Guyane (UAG) - Institut National de la Santé et de la Recherche Médicale (INSERM) - CHU de Pointe-à-Pitre - Centre Hospitalier de Cayenne Andrée Rosemon - CHU de Fort de France</contributor>
<description>International audience</description>
<source>ISSN: 0956-4624</source>
<source>EISSN: 0956-4624</source>
<source>International Journal of STD and AIDS</source>
<publisher>SAGE Publications</publisher>
<identifier>inserm-01082409</identifier>
<identifier>http://www.hal.inserm.fr/inserm-01082409</identifier>
<identifier>http://www.hal.inserm.fr/inserm-01082409/document</identifier>
<identifier>http://www.hal.inserm.fr/inserm-01082409/file/2014%2C%20Vantilcke%20-%20Fever%20and%20HIV.pdf</identifier>
<identifier>http://www.hal.inserm.fr/inserm-01082409/file/Histoplasmosis_tab_2%5B1%5D%20revised.pdf</identifier>
<identifier>http://www.hal.inserm.fr/inserm-01082409/file/Fig%201%20histo%20vincent.pdf</identifier>
<identifier>http://www.hal.inserm.fr/inserm-01082409/file/Table%201%20histo%20vincent%20revision2.pdf</identifier>
<identifier>http://www.hal.inserm.fr/inserm-01082409/file/fig%202%20vincent%20histo.pdf</identifier>
<source>http://www.hal.inserm.fr/inserm-01082409</source>
<source>International Journal of STD and AIDS, SAGE Publications, 2014, 25, pp.656 - 661. 〈10.1177/0956462413516299〉</source>
<identifier>DOI : 10.1177/0956462413516299</identifier>
<relation>info:eu-repo/semantics/altIdentifier/doi/10.1177/0956462413516299</relation>
<identifier>PUBMED : 24598976</identifier>
<relation>info:eu-repo/semantics/altIdentifier/pmid/24598976</relation>
<language>en</language>
<subject lang=en>Fever</subject>
<subject lang=en>histoplasmosis</subject>
<subject lang=en>primary prophylaxis</subject>
<subject lang=en>French Guiana</subject>
<subject lang=en>HIV</subject>
<subject>[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie</subject>
<type>info:eu-repo/semantics/article</type>
<type>Journal articles</type>
<description lang=en>In Western French Guiana there was a dramatic increase in HIV-prevalence between 1990 and 2000. The present study describes the causes of fever among HIV patients hospitalized in the medical ward of the only hospital in the western part of French Guiana. A retrospective descriptive study was conducted between January 1st 2008 and June 30th 2010 in the department of medicine of Saint Laurent du Maroni Hospital. The main characteristics of 67 patients having presented with fever in the first 48 hours of hospitalization were described. Among patients with CD4<200/mm3 the main febrile opportunistic infection was disseminated histoplasmosis (41.1%). Among patients with CD4 counts <50/mm3 and fever without focal points 85.7% had disseminated histoplasmosis. Three patients died and all had disseminated histoplasmosis. Disseminated histoplasmosis is the most common febrile opportunistic infection in western French Guiana. Primary prophylaxis with itraconazole among immunocompromised patients seems warranted.</description>
<date>2014-03-04</date>
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