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<datestamp>2017-12-21</datestamp>
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<publisher>HAL CCSD</publisher>
<title lang=en>Hierarchy of Determinants Underlying Death among HIV-Infected Patients in French Guiana</title>
<creator>Hanf, Matthieu</creator>
<creator>Adenis, Antoine</creator>
<creator>Carme, Bernard</creator>
<creator>Couppié, Pierre</creator>
<creator>Nacher, Mathieu</creator>
<contributor>EA 3593 Université des Antilles et de la Guyane ; Centre d'investigation clinique Antilles-Guyane ; Institut National de la Santé et de la Recherche Médicale (INSERM) - CH Cayenne - Institut National de la Santé et de la Recherche Médicale (INSERM) - CH Cayenne - Epidémiologie des parasitoses et mycoses tropicales ; Université des Antilles et de la Guyane (UAG) - Institut National de la Santé et de la Recherche Médicale (INSERM) - Université des Antilles et de la Guyane (UAG) - Institut National de la Santé et de la Recherche Médicale (INSERM)</contributor>
<contributor>EA 3593 Université des Antilles et de la Guyane ; Centre d'investigation clinique Antilles-Guyane ; Institut National de la Santé et de la Recherche Médicale (INSERM) - CH Cayenne - Institut National de la Santé et de la Recherche Médicale (INSERM) - CH Cayenne</contributor>
<contributor>Centre d'investigation clinique Antilles-Guyane ; Institut National de la Santé et de la Recherche Médicale (INSERM) - CH Cayenne</contributor>
<contributor>Epidémiologie des parasitoses et mycoses tropicales ; Université des Antilles et de la Guyane (UAG) - Institut National de la Santé et de la Recherche Médicale (INSERM)</contributor>
<contributor>Service de Dermatologie et Vénérologie ; Centre Hospitalier de Cayenne Andrée Rosemon</contributor>
<description>International audience</description>
<source>J AIDS Clinic Res</source>
<identifier>inserm-00914956</identifier>
<identifier>http://www.hal.inserm.fr/inserm-00914956</identifier>
<identifier>http://www.hal.inserm.fr/inserm-00914956/document</identifier>
<identifier>http://www.hal.inserm.fr/inserm-00914956/file/2012_Hanf_-_Hierarchysur Determinants_Underlying_Death_among_HIV-Infected_patients_in_French_Guiana.pdf</identifier>
<source>http://www.hal.inserm.fr/inserm-00914956</source>
<source>J AIDS Clinic Res, 2012, 3 (7), pp.1000172. 〈10.4172/2155-6113.1000172〉</source>
<identifier>DOI : 10.4172/2155-6113.1000172</identifier>
<relation>info:eu-repo/semantics/altIdentifier/doi/10.4172/2155-6113.1000172</relation>
<language>en</language>
<subject lang=en>HIV/AIDS</subject>
<subject lang=en>Mortality</subject>
<subject lang=en>Female</subject>
<subject lang=en>Addiction</subject>
<subject lang=en>Epidemiology</subject>
<subject lang=en>Risk factor</subject>
<subject lang=en>French Guiana</subject>
<subject lang=en>Tree based method</subject>
<subject>[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie</subject>
<type>info:eu-repo/semantics/article</type>
<type>Journal articles</type>
<description lang=en>Objective: In order to determine how risk factors of death among HIV-infected patients in French Guiana interact with one another and to define high risk population segments, an alternative statistical method to Cox proportional hazards models was used. Patients and methods: Data from HIV+ patients followed in the three main hospitals of French Guiana were used. Data were extracted from the prospective French Hospital Database for HIV (FHDH). To examine the nature of the relationships between time of death since the first consultation and a set of predictor variables (age at enrolment, gender, nationality, CD4 count at enrolment, presence or absence of HAART at enrolment, a declared addiction, and mode of acquisition of the virus) a survival tree analysis was used. Survival rates at 5 years and 10 years and their 95% confidence interval were also calculated. Results: This analysis permitted to reveal a new specific subgroup of HIV+ patients particularly at risk in French Guiana not already mentioned in the literature: the HIV+ female patients with a declared addiction. Conclusions: Prevention and care in this vulnerable segment of the HIV+ population identified by this methodology should be reinforced.</description>
<date>2012-09-26</date>
<rights>info:eu-repo/semantics/OpenAccess</rights>
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