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<title lang=en>Aedes aegypti larvicidal sesquiterpene alkaloids from Maytenus oblongata</title>
<creator>Touré, Seindé</creator>
<creator>Nirma, Charlotte</creator>
<creator>Falkowski, Michael</creator>
<creator>Dusfour, Isabelle</creator>
<creator>Boulogne, Isabelle</creator>
<creator>Jahn-Oyac, Arnaud</creator>
<creator>Coke, Maïra</creator>
<creator>Azam, Didier</creator>
<creator>Girod, Romain</creator>
<creator>Moriou, Céline</creator>
<creator>Odonne, Guillaume</creator>
<creator>Stien, Didier</creator>
<creator>Houël, Emeline</creator>
<creator>Eparvier, Véronique</creator>
<contributor>Institut de Chimie des Substances Naturelles ; Centre National de la Recherche Scientifique (CNRS)</contributor>
<contributor>Ecologie des forêts de Guyane (ECOFOG) ; Centre de Coopération Internationale en Recherche Agronomique pour le Développement (CIRAD) - Institut National de la Recherche Agronomique (INRA) - Université des Antilles et de la Guyane (UAG) - AgroParisTech - Université de Guyane (UG) - Centre National de la Recherche Scientifique (CNRS)</contributor>
<contributor>Institut Pasteur de la Guyane Française ; Institut Pasteur de la Guyane - Réseau International des Instituts Pasteur (RIIP)</contributor>
<contributor>Laboratoire de Glycobiologie et Matrice Extracellulaire Végétale (Glyco-MEV) ; Université de Rouen Normandie (URN) ; Normandie Université (NU) - Normandie Université (NU)</contributor>
<contributor>Unité d'Ecologie et Ecotoxicologie Aquatiques (UEEA) ; Institut National de la Recherche Agronomique (INRA)</contributor>
<contributor> Laboratoire Ecologie, Evolution, Interactions des Systèmes Amazoniens (LEEISA) ; Centre National de la Recherche Scientifique (CNRS)</contributor>
<contributor>Laboratoire de Biodiversité et Biotechnologies Microbiennes (LBBM) ; Université Pierre et Marie Curie - Paris 6 (UPMC) - PIERRE FABRE - Electricité de France Recherche et Développement (EDF R&D) - Centre National de la Recherche Scientifique (CNRS)</contributor>
<source>ISSN: 0163-3864</source>
<source>EISSN: 1520-6025</source>
<source>Journal of Natural Products</source>
<publisher>American Chemical Society</publisher>
<identifier>hal-01603411</identifier>
<identifier>https://hal.archives-ouvertes.fr/hal-01603411</identifier>
<source>https://hal.archives-ouvertes.fr/hal-01603411</source>
<source>Journal of Natural Products, American Chemical Society, 2017, 80 (2), pp.384-390. 〈10.1021/acs.jnatprod.6b00850〉</source>
<identifier>DOI : 10.1021/acs.jnatprod.6b00850</identifier>
<relation>info:eu-repo/semantics/altIdentifier/doi/10.1021/acs.jnatprod.6b00850</relation>
<identifier>PUBMED : 28186749</identifier>
<relation>info:eu-repo/semantics/altIdentifier/pmid/28186749</relation>
<identifier>PRODINRA : 406747</identifier>
<language>en</language>
<subject>[SDV] Life Sciences [q-bio]</subject>
<type>info:eu-repo/semantics/article</type>
<type>Journal articles</type>
<description lang=en>Four new sesquiterpene alkaloids (1-4) with a β-dihydroagrofuran skeleton and a new triterpenoid (5) were isolated from an ethyl acetate extract of Maytenus oblongata stems. Their structures were elucidated using 1D and 2D NMR spectroscopy as well as MS and ECD experiments. The M. oblongata stem EtOAc extract and the pure compounds isolated were tested for larvicidal activity against Aedes aegypti under laboratory conditions, and compounds 2 and 3 were found to be active.</description>
<date>2017</date>
</dc>
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