untitled
<OAI-PMH schemaLocation=http://www.openarchives.org/OAI/2.0/ http://www.openarchives.org/OAI/2.0/OAI-PMH.xsd>
<responseDate>2018-01-15T18:22:07Z</responseDate>
<request identifier=oai:HAL:hal-01359566v1 verb=GetRecord metadataPrefix=oai_dc>http://api.archives-ouvertes.fr/oai/hal/</request>
<GetRecord>
<record>
<header>
<identifier>oai:HAL:hal-01359566v1</identifier>
<datestamp>2017-12-21</datestamp>
<setSpec>type:ART</setSpec>
<setSpec>subject:sdv</setSpec>
<setSpec>collection:UNIV-RENNES1</setSpec>
<setSpec>collection:IRSET</setSpec>
<setSpec>collection:UNIV-AG</setSpec>
<setSpec>collection:IRSET-VCER</setSpec>
<setSpec>collection:IFR140</setSpec>
<setSpec>collection:BIOSIT</setSpec>
<setSpec>collection:GIP-BE</setSpec>
<setSpec>collection:UR1-HAL</setSpec>
<setSpec>collection:EHESP</setSpec>
<setSpec>collection:UR1-UFR-SVE</setSpec>
<setSpec>collection:USPC</setSpec>
<setSpec>collection:STATS-UR1</setSpec>
<setSpec>collection:UR1-SDV</setSpec>
<setSpec>collection:IRSET-8</setSpec>
<setSpec>collection:UNIV-ANGERS</setSpec>
<setSpec>collection:IRSET-EHESP</setSpec>
</header>
<metadata><dc>
<publisher>HAL CCSD</publisher>
<title lang=en>Analgesic use - prevalence, biomonitoring and endocrine and reproductive effects</title>
<creator>Kristensen, David M.</creator>
<creator>Mazaud-Guittot, Sverine</creator>
<creator>Gaudriault, Pierre</creator>
<creator>Lesné, Laurianne</creator>
<creator>Serrano, Tania</creator>
<creator>Main, Katharina M.</creator>
<creator>Jégou, Bernard</creator>
<contributor>Department of Growth and Reproduction ; University of Copenhagen (KU)</contributor>
<contributor>Institut de recherche, santé, environnement et travail [Rennes] (Irset) ; Université d'Angers (UA) - Université des Antilles et de la Guyane (UAG) - Université de Rennes 1 (UR1) - École des Hautes Études en Santé Publique [EHESP] (EHESP) - Institut National de la Santé et de la Recherche Médicale (INSERM) - Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )</contributor>
<contributor>École des Hautes Études en Santé Publique [EHESP] (EHESP)</contributor>
<contributor>Danish Council for Independent Research (Medical Sciences)</contributor>
<contributor> Fondation pour la Recherche Medicale</contributor>
<contributor> Inserm (Institut national de la sante et de la recherche medicale)</contributor>
<contributor> Rennes 1 University</contributor>
<contributor> EHESP-School of Public Health</contributor>
<contributor> ANSM (Agence Nationale de la Securite du Medicament) [AAP-2012-037, HAP-2014-073]</contributor>
<description>International audience</description>
<source>Nature Reviews Endocrinology</source>
<identifier>hal-01359566</identifier>
<identifier>https://hal-univ-rennes1.archives-ouvertes.fr/hal-01359566</identifier>
<source>https://hal-univ-rennes1.archives-ouvertes.fr/hal-01359566</source>
<source>Nature Reviews Endocrinology, 2016, 12 (7), pp.381--393. 〈10.1038/nrendo.2016.55〉</source>
<identifier>DOI : 10.1038/nrendo.2016.55</identifier>
<relation>info:eu-repo/semantics/altIdentifier/doi/10.1038/nrendo.2016.55</relation>
<identifier>PUBMED : 27150289</identifier>
<relation>info:eu-repo/semantics/altIdentifier/pmid/27150289</relation>
<language>en</language>
<subject lang=en>nonsteroidal antiinflammatory drugs</subject>
<subject lang=en> prenatal paracetamol exposure</subject>
<subject lang=en> over-the-counter</subject>
<subject lang=en> low-dose aspirin</subject>
<subject lang=en> persistent pulmonary-hypertension</subject>
<subject lang=en> blood-plasma levels</subject>
<subject lang=en> acetylsalicylic-acid</subject>
<subject lang=en> n-acetyl-4-aminophenol paracetamol</subject>
<subject lang=en> intrauterine exposure</subject>
<subject lang=en> postmenopausal women</subject>
<subject>[SDV.EE.SANT] Life Sciences [q-bio]/Ecology, environment/Health</subject>
<type>info:eu-repo/semantics/article</type>
<type>Journal articles</type>
<description lang=en>Paracetamol and NSAIDs, in particular acetylsalicylic acid (aspirin) and ibuprofen, are among the most used and environmentally released pharmaceutical drugs. The differences in international trends in the sale and consumption of mild analgesics reflect differences in marketing, governmental policies, habits, accessibility, disease patterns and the age distribution of each population. Biomonitoring indicates ubiquitous and high human exposure to paracetamol and to salicylic acid, which is the main metabolite of acetylsalicylic acid. Furthermore, evidence suggests that analgesics can have endocrine disruptive properties capable of altering animal and human reproductive function from fetal life to adulthood in both sexes. Medical and public awareness about these health concerns should be increased, particularly among pregnant women.</description>
<date>2016</date>
</dc>
</metadata>
</record>
</GetRecord>
</OAI-PMH>
