untitled
<OAI-PMH schemaLocation=http://www.openarchives.org/OAI/2.0/ http://www.openarchives.org/OAI/2.0/OAI-PMH.xsd>
<responseDate>2018-01-15T15:42:23Z</responseDate>
<request identifier=oai:HAL:hal-00384338v1 verb=GetRecord metadataPrefix=oai_dc>http://api.archives-ouvertes.fr/oai/hal/</request>
<GetRecord>
<record>
<header>
<identifier>oai:HAL:hal-00384338v1</identifier>
<datestamp>2018-01-11</datestamp>
<setSpec>type:ART</setSpec>
<setSpec>collection:CIRAD</setSpec>
<setSpec>collection:CNRS</setSpec>
<setSpec>collection:UNIV-AG</setSpec>
<setSpec>collection:UNIV-TLSE3</setSpec>
<setSpec>collection:AGROPARISTECH</setSpec>
<setSpec>collection:INRA</setSpec>
<setSpec>collection:ECOFOG</setSpec>
</header>
<metadata><dc>
<publisher>HAL CCSD</publisher>
<title lang=en>Quassia amara L. (Simaroubaceae) leaf tea: Effect of the growing stage and desiccation status on the antimalarial activity of a traditional preparation</title>
<creator>Bertani, Stephane</creator>
<creator>Houel, Emeline</creator>
<creator>Bourdy, Genevieve</creator>
<creator>Stien, Didier</creator>
<creator>Jullian, Valérie</creator>
<creator>Landau, Irene</creator>
<creator>Deharo, Eric</creator>
<contributor>laboratoire de parasitologie comparée et modèles expérimentaux</contributor>
<contributor>Ecologie des forêts de Guyane (ECOFOG) ; Centre de Coopération Internationale en Recherche Agronomique pour le Développement (CIRAD) - Institut National de la Recherche Agronomique (INRA) - Université des Antilles et de la Guyane (UAG) - AgroParisTech - Centre National de la Recherche Scientifique (CNRS)</contributor>
<contributor>faculte des sciences pharmaceutiques (umr 152 IRD) ; Faculte des Sciences Pharmaceutiques</contributor>
<contributor>Pharmacochimie des substances naturelles et pharmacophores redox ; Université Paul Sabatier - Toulouse 3 (UPS)</contributor>
<description>International audience</description>
<source>ISSN: 0378-8741</source>
<source>Journal of Ethnopharmacology</source>
<publisher>Elsevier</publisher>
<identifier>hal-00384338</identifier>
<identifier>https://hal.archives-ouvertes.fr/hal-00384338</identifier>
<source>https://hal.archives-ouvertes.fr/hal-00384338</source>
<source>Journal of Ethnopharmacology, Elsevier, 2007, 111, pp.40-42. 〈10.1016/j.jep.2006.10.028〉</source>
<identifier>DOI : 10.1016/j.jep.2006.10.028</identifier>
<relation>info:eu-repo/semantics/altIdentifier/doi/10.1016/j.jep.2006.10.028</relation>
<language>en</language>
<subject lang=it>Antimalarial</subject>
<subject lang=it>Quassia amara</subject>
<subject lang=it>Quassinoids</subject>
<subject lang=it>Simalikalactone D</subject>
<subject lang=it>Traditional medicine</subject>
<type>info:eu-repo/semantics/article</type>
<type>Journal articles</type>
<description lang=en>In French Guiana, Quassia amara L. (Simaroubaceae) leaf tea is a well-known widely used traditional antimalarial remedy. Impact of the vegetal sampling condition on in vivo and in vitro antimalarial activity was assessed. Traditional infusions were prepared with juvenile or mature leaves, both either fresh or dried. Results showed that growing stage and freshness of vegetal material exert a striking effect on antimalarial activity, both in vitro and in vivo. By far, leaf tea made from fresh juvenile (FJ) Quassia amara leaves was the most active. In vitro, active component (simalikalactone D) concentration correlates biological activities, although unexplained subtle variations were observed. In vivo, tea made with dried juvenile (DJ) leaves displays a peculiar behavior, meaning that some components may help simalikalactone D delivery or may be active in vivo only, therefore enhancing the expected curative effect of the traditional preparation.</description>
<date>2007</date>
</dc>
</metadata>
</record>
</GetRecord>
</OAI-PMH>
