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<OAI-PMH schemaLocation=http://www.openarchives.org/OAI/2.0/ http://www.openarchives.org/OAI/2.0/OAI-PMH.xsd> <responseDate>2018-01-15T18:17:44Z</responseDate> <request identifier=oai:HAL:hal-01509563v1 verb=GetRecord metadataPrefix=oai_dc>http://api.archives-ouvertes.fr/oai/hal/</request> <GetRecord> <record> <header> <identifier>oai:HAL:hal-01509563v1</identifier> <datestamp>2018-01-11</datestamp> <setSpec>type:ART</setSpec> <setSpec>subject:sdv</setSpec> <setSpec>collection:CNRS</setSpec> <setSpec>collection:UNIV-AG</setSpec> <setSpec>collection:UNIV-FCOMTE</setSpec> <setSpec>collection:UNIV-PARIS5</setSpec> <setSpec>collection:UNIV-PARIS7</setSpec> <setSpec>collection:CGE</setSpec> <setSpec>collection:RIIP</setSpec> <setSpec>collection:RIIP_DAKAR</setSpec> <setSpec>collection:APHP</setSpec> <setSpec>collection:HL</setSpec> <setSpec>collection:UNIV-RENNES1</setSpec> <setSpec>collection:UNIV-LORRAINE</setSpec> <setSpec>collection:UR1-HAL</setSpec> <setSpec>collection:USPC</setSpec> <setSpec>collection:UR1-SDV</setSpec> <setSpec>collection:CHRONO-ENVIRONNEMENT</setSpec> </header> <metadata><dc> <publisher>HAL CCSD</publisher> <title lang=en>Time interval between infective endocarditis first symptoms and diagnosis: relationship to infective endocarditis characteristics, microorganisms and prognosis.</title> <creator>N’Guyen, Yohan</creator> <creator>Duval, Xavier</creator> <creator>Revest, Matthieu</creator> <creator>Saada, Matthieu</creator> <creator>Erpelding, Marie-Line</creator> <creator>Selton-Suty, Christine</creator> <creator>Bouchiat, Coralie</creator> <creator>Delahaye, François</creator> <creator>Chirouze, Catherine</creator> <creator>Alla, François</creator> <creator>Strady, Christophe</creator> <creator>Hoen, Bruno</creator> <creator>N'Guyen, Yohan</creator> <contributor>Modèles et méthodes de l'évaluation thérapeutique des maladies chroniques ; Université Paris Diderot - Paris 7 (UPD7) - Institut National de la Santé et de la Recherche Médicale (INSERM)</contributor> <contributor>INSERA CIC ; Hôpital Bichat - Claude Bernard ; Assistance publique - Hôpitaux de Paris (AP-HP) - Hôpital Bichat - Claude Bernard [Paris] - Université Paris Diderot - Paris 7 (UPD7) - Assistance publique - Hôpitaux de Paris (AP-HP) - Hôpital Bichat - Claude Bernard [Paris] - Université Paris Diderot - Paris 7 (UPD7)</contributor> <contributor>Service des maladies infectieuses et réanimation médicale ; Université de Rennes 1 (UR1) - Hôpital Pontchaillou</contributor> <contributor>Maladies chroniques, santé perçue, et processus d'adaptation. Approches épidémiologiques et psychologiques. (APEMAC - EA 4360) ; Université Paris Descartes - Paris 5 (UPD5) - Université de Lorraine (UL)</contributor> <contributor>Centre d'Investigation Clinique - Epidemiologie Clinique/essais Cliniques Nancy ; Cancéropôle du Grand Est - Institut National de la Santé et de la Recherche Médicale (INSERM)</contributor> <contributor>Institut Lorrain du Coeur et des Vaisseaux Louis Mathieu [Nancy]</contributor> <contributor>Institut Pasteur de Dakar ; Institut Pasteur de Dakar - Réseau International des Instituts Pasteur (RIIP)</contributor> <contributor>Laboratoire Chrono-environnement (LCE) ; Université Bourgogne Franche-Comté (UBFC) - Université de Franche-Comté (UFC) - Centre National de la Recherche Scientifique (CNRS)</contributor> <contributor>Service des maladies infectieuses et tropicales ; Centre Hospitalier Régional Universitaire [Besançon] (CHRU Besançon) - Hôpital Saint-Jacques</contributor> <contributor>Centre Hospitalier Régional Universitaire [Besançon] (CHRU Besançon)</contributor> <contributor>Centre d'Investigation Clinique - Innovation Technologique (CIC-IT) ; Centre Hospitalier Régional Universitaire de Nancy (CHRU Nancy)</contributor> <contributor>CHU Reims</contributor> <contributor>Centre d'Investigation Clinique Antilles-Guyane (CIC - Antilles Guyane) ; Université des Antilles et de la Guyane (UAG) - Institut National de la Santé et de la Recherche Médicale (INSERM) - CHU de Pointe-à-Pitre - Centre Hospitalier de Cayenne Andrée Rosemon - CHU de Fort de France</contributor> <description>International audience</description> <source>ISSN: 0785-3890</source> <source>Annals of Medicine</source> <publisher>Taylor & Francis</publisher> <identifier>hal-01509563</identifier> <identifier>https://hal.archives-ouvertes.fr/hal-01509563</identifier> <source>https://hal.archives-ouvertes.fr/hal-01509563</source> <source>Annals of Medicine, Taylor & Francis, 2017, 49 (2), pp.117-125</source> <identifier>PUBMED : 27607562</identifier> <relation>info:eu-repo/semantics/altIdentifier/pmid/27607562</relation> <language>en</language> <subject lang=en>Infective endocarditis</subject> <subject lang=en>acute</subject> <subject lang=en>cardiac surgery</subject> <subject lang=en>chronic</subject> <subject lang=en>mortality</subject> <subject lang=en>prognosis</subject> <subject lang=en>septic shock</subject> <subject lang=en>stroke</subject> <subject>[SDV.MHEP] Life Sciences [q-bio]/Human health and pathology</subject> <type>info:eu-repo/semantics/article</type> <type>Journal articles</type> <description lang=0>To analyze the characteristics and outcome of infective endocarditis (IE) according to the time interval between IE first symptoms and diagnosis.</description> <description lang=1>Among the IE cases of a French population-based epidemiological survey, patients having early-diagnosed IE (diagnosis of IE within 1 month of first symptoms) were compared with those having late-diagnosed IE (diagnosis of IE more than 1 month after first symptoms).</description> <description lang=2>Among the 486 definite-IE, 124 (25%) had late-diagnosed IE whereas others had early-diagnosed IE. Early-diagnosed IE were independently associated with female gender (OR = 1.8; 95% CI [1.0-3.0]), prosthetic valve (OR= 2.6; 95% CI [1.4-5.0]) and staphylococci as causative pathogen (OR = 3.7; 95% CI [2.2-6.2]). Cardiac surgery theoretical indication rates were not different between early and late-diagnosed IE (56.3% vs 58.9%), whereas valve surgery performance was lower in early-diagnosed IE (41% vs 53%; p = .03). In-hospital mortality rates were higher in early-diagnosed IE than in late-diagnosed IE (25.1% vs 16.1%; p < .001).</description> <description lang=3>The time interval between IE first symptoms and diagnosis is closely related to the IE clinical presentation, patient characteristics and causative microorganism. Better prognosis reported in late-diagnosed IE may be related to a higher rate of valvular surgery. KEY MESSAGES Infective endocarditis, which time interval between first symptoms and diagnosis was less than one month, were mainly due to Staphylococcus aureus in France. Staphylococcus aureus infective endocarditis were associated with septic shock, transient ischemic attack or stroke and higher mortality rates than infective endocarditis due to other bacteria or infective endocarditis, which time interval between first symptoms and diagnosis was more than one month. Infective endocarditis, which time interval between first symptoms and diagnosis was more than one month, were accounting for one quarter of all infective endocarditis in our study and were associated with vertebral osteomyelitis and a higher rate of cardiac surgery performed for hemodynamic indication than other infective endocarditis.</description> <date>2017</date> </dc> </metadata> </record> </GetRecord> </OAI-PMH>