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<identifier>oai:HAL:hal-00916684v1</identifier>
<datestamp>2015-02-20</datestamp>
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<metadata><dc>
<publisher>HAL CCSD</publisher>
<title lang=fr>Impact des facteurs environnementaux physiques et chimiques sur le déroulement et les issues de grossesse. [Impact of chemical and physical environmental factors on the course and outcome of pregnancy.]</title>
<creator>Slama, Rémy</creator>
<creator>Cordier, Sylvaine</creator>
<contributor>Epidémiologie environnementale appliquée à la reproduction et la santé respiratoire ; Institut d'oncologie/développement Albert Bonniot de Grenoble ; INSERM - CHU Grenoble - EFS - Université Joseph Fourier (Grenoble 1 UJF) - INSERM - CHU Grenoble - EFS - Université Joseph Fourier (Grenoble 1 UJF)</contributor>
<contributor>Recherches épidémiologiques sur l'environnement, la reproduction et le développement ; Institut de recherche, santé, environnement et travail [Rennes] (Irset) ; INSERM - École Nationale de la Santé Publique - Université de Rennes 1 (UR1) - Université des Antilles et de la Guyane (UAG) - Structure Fédérative de Recherche en Biologie-Santé de Rennes (Biosit) ; Université de Rennes 1 (UR1) - INSERM - CNRS - INSERM - CNRS - INSERM - École Nationale de la Santé Publique - Université de Rennes 1 (UR1) - Université des Antilles et de la Guyane (UAG) - Structure Fédérative de Recherche en Biologie-Santé de Rennes (Biosit) ; Université de Rennes 1 (UR1) - INSERM - CNRS - INSERM - CNRS</contributor>
<description>Publié en septembre 2013 dans le "Journal de Gynécologie Obstétrique et Biologie de la Reproduction" vol.42 n°5 p.413-444</description>
<identifier>hal-00916684</identifier>
<identifier>https://hal.archives-ouvertes.fr/hal-00916684</identifier>
<identifier>https://hal.archives-ouvertes.fr/hal-00916684/document</identifier>
<source>https://hal.archives-ouvertes.fr/hal-00916684</source>
<source>Publié en septembre 2013 dans le "Journal de Gynécologie Obstétrique et Biologie de la Reproducti.. 2012</source>
<identifier>DOI : 10.1016/j.jgyn.2013.02.012</identifier>
<language>fr</language>
<subject lang=fr>Grossesse</subject>
<subject lang=fr>Cohorte</subject>
<subject lang=fr>Environnement</subject>
<subject lang=fr>Épidémiologie</subject>
<subject lang=fr>Fœtus</subject>
<subject>[SDV.SPEE] Life Sciences/Santé publique et épidémiologie</subject>
<type>Preprints, Working Papers, ...</type>
<description lang=en>We review the epidemiological literature on the possible impact of chemical and physical factors on pregnancy outcome. Effects of in-utero exposures on child health are not considered here. The highest levels of evidence concern the effects of passive smoking (on fetal growth), of lead (pregnancy-induced hypertension, fetal growth), of some Polychlorinated Biphenyls (PCB; on fetal growth) and, to a lesser extent, of atmospheric pollutants (on fetal growth and preterm delivery). For the other compounds, in particular non-persistent chemicals, the literature, which is generally based on poor exposure assessment, is less informative. In conclusion, the last decades have witnessed the development of mother-child cohorts in which exposure biomarkers have been assayed, allowing a large number of publications. For some persistent compounds, for which efficient exposure assessment approaches have been used, the literature indicates a likely impact on pregnancy outcomes. With the exception of air pollutants, the literature on non-persistent compounds is little conclusive; the assay of exposure biomarkers in repeated biological samples collected at relevant time points could help further increase knowledge regarding any health impact.</description>
<date>2012-10-16</date>
</dc>
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