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<datestamp>2017-12-21</datestamp>
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<publisher>HAL CCSD</publisher>
<title lang=fr>Aide à l’activation ovocytaire : Un nouvel atout dans le traitement des infertilités masculines sévères [Assisted oocyte activation: a new tool for severe male factor infertility treatment]</title>
<creator>Ravel, Célia</creator>
<creator>Kazdar, Nadia</creator>
<creator>Drapier, Hortense</creator>
<creator>Duros, Solène</creator>
<creator>Viard, Patricia</creator>
<contributor>CHU Pontchaillou [Rennes]</contributor>
<contributor>Institut de recherche, santé, environnement et travail [Rennes] (Irset) ; Université d'Angers (UA) - Université des Antilles et de la Guyane (UAG) - Université de Rennes 1 (UR1) - École des Hautes Études en Santé Publique [EHESP] (EHESP) - Institut National de la Santé et de la Recherche Médicale (INSERM) - Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )</contributor>
<description>National audience</description>
<source>Médecine Sciences: M/S</source>
<identifier>hal-01286256</identifier>
<identifier>https://hal-univ-rennes1.archives-ouvertes.fr/hal-01286256</identifier>
<source>https://hal-univ-rennes1.archives-ouvertes.fr/hal-01286256</source>
<source>Médecine Sciences: M/S, 2016, 32 (2), pp.198--203. 〈10.1051/medsci/20163202014〉</source>
<identifier>DOI : 10.1051/medsci/20163202014</identifier>
<relation>info:eu-repo/semantics/altIdentifier/doi/10.1051/medsci/20163202014</relation>
<identifier>PUBMED : 26936178</identifier>
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<language>fr</language>
<subject>[SDV] Life Sciences [q-bio]</subject>
<type>info:eu-repo/semantics/article</type>
<type>Journal articles</type>
<description lang=fr>In severe male infertility, in vitro fertilization (IVF) with intra-cytoplasmic sperm injection (ICSI) represents the sole available therapeutic option. However this technique is not always successful in promoting fertilization, as some couples completely and repeatedly fail to obtain any embryo. In many cases, this failure can be attributed to a defective rise in intracellular calcium, which is required to achieve oocyte activation. Over the last twenty years, several laboratories dedicated to assisted reproduction technologies have been using a calcium ionophore to assist oocyte activation. The aim of this review is to give an overview of the advances and consequences associated with this new technique referred to as assisted oocyte activation</description>
<date>2016-02</date>
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